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440 ATP7B encodes a transmembrane copper transport ATPase, and mutations in ATP7B cause Wilsons disease by impairing copper homeostasis, leading to copper overload in the liver, brain, and other organs

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The Botox typically takes about 1-2 weeks to start kicking in, but the addition of a numbing medicine can provide some temporary relief as the Botox is slowly kicking in

The energy and cognitive benefits are well-reported anecdotally and in smaller human trials, with larger trials currently underway