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These typically resolve within the first week

Gallbladder Disease - High amounts of niacin could worsen this condition

Once treatment has started and the patient responds (symptoms resolve, blood counts normalize), B12 levels no longer correlate well with tissue sufficiency because circulating B12 can be very high after injections

Low levels of Vitamin B12 have been associated with an increased risk of mood disorders such as depression and anxiety

Many individuals who struggle with stress and anxiety have found that B12 supplementation helps them manage their emotions more effectively and feel calmer throughout the day

doi: 10.3389/fendo.2018.00035