Conversely, Wang et al
And it is related to cholesterol metabolism genes such as LXR, ATP-binding cassette transporter A1 (ABCA1), ATP-binding cassette G1 (ABCG1), acyl-coenzyme A oxidase 1 (ACOX1), apolipoprotein AI (apo AI) (Fig
Source: Hwang, et al JAMA Health Forum March 14, 2025 Researchers from the University of Chicago modeled the clinical and financial impact of anti-obesity medications: Zepbound (tirzepatide), Wegovy (semaglutide), and two oral generic drug combinations, phentermine-topiramate and naltrexone-bupropion
The immunohistochemical results demonstrated a significant reduction in 4-HNE in the semaglutide group compared to the I/R group (Figures 4A, B)
Don't judge results at week 3
If you have any doubts, consult with your healthcare provider to get the right advice