However, they are still subject to state board of pharmacy oversight and must comply with USP compounding standards and Sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act, according to the Alliance for Pharmacy Compounding
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The question that matters is whether those ingredients can be absorbed through the skin in amounts sufficient to have any effect
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doi:10.1056/NEJMoa0802743 2
Chili peppers can also irritate human skin, and excessive intake can cause nausea, vomiting, abdominal pain and burning, diarrhea