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The company plans to resubmit the application for neffy in the first half of next year and anticipates another FDA action date in the second half of 2024
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The clinical study reveals that the reduced blood glucose and elevated risk of hypoglycemia are present in LQT2 patients because of increased secretion of GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide) and insulin, as well as lowered glucagon secretion, which is resulting from loss-of-function mutations in hERG channels (Hyltn-Cavallius et al., 2017)
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