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Both semaglutide and tirzepatide slow how quickly your stomach empties, so the hydration approach is the same on either one: steady fluid through the day, with a little extra during dose increases or any nausea
ChemTexts 5:9 Bai J, Cederbaum AI (2001) Mitochondrial catalase and oxidative injury
It can affect anyone, regardless of age or background
High-dose oral B12 (1,000 to 2,000 mcg daily) can actually correct deficiency even in some people with poor absorption, because a small percentage of B12 is absorbed passively (without intrinsic factor)