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Gclc w/f or Gclc w/w mice (Gclc WT) and Gclc f/f mice (hereafter referred to as Gclc L-KO) were monitored following tail-vein injection with AAV-TBG-Cre (Fig

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While laboratory findings and observational studies suggest potential benefits against the biological drivers of dementia, results from large clinical trials in people with established Alzheimers are still inconclusive