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Vegetarian diets in the Adventist Health Study 2: a review of initial published findings

The authors concluded that the safety profile of AOD9604 was equivalent to the placebo

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Specifically, the biosynthesis of amino acids (37 KOs), was significantly down-represented, including cysteine and methionine metabolism ( metA , metB , metK , mtnN , thrB , cysK , patB and L-serine dehydratase ), the biosynthesis of lysine ( dapA , dapB , dapE , dapH , dapL , argD , patA and lysA ), the metabolism of histidine ( hisA , hisB , hisE , hisH and hisI ), glycine, serine and threonine ( glyA , thrB , thrC and L-serine dehydratase ), alanine, aspartate and glutamate (asnA, asnB and argH), the biosynthesis of phenylalanine, tyrosine and tryptophan ( aroD and aroE ) and the biosynthesis of arginine ( argD and argH )