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(2007) GPR39 signaling is stimulated by zinc ions but not by obestatin

All data generated or analyzed during this study are included in this published article (and its Supplementary Information files)

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However, this outcome fell short of the anticipated 25% weight reduction, potentially limiting its competitive edge against Eli Lillys ZEPBOUND, which reported up to 20.9% weight loss in the SURMOUNT-1 trial. In the subsequent REDEFINE 2 trial, which focused on adults with obesity or overweight and type 2 diabetes, CagriSema achieved a 15.7% mean weight loss after 68 weeks, compared to 3.1% with placebo

After reconstitution with sterile solvents, the compound should be stored at 2C to 8C

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