dupixent and tirzepatide Dupilumab New Eczema Drug Dupixent Approved

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The autonomic nervous system (ANS), particularly the parasympathetic vagus nerve, plays a crucial role in the neural regulation of obesity

A Bayesian hierarchical model was fitted using the brms framework, specifying percent weight change as a Gaussian outcome with (i) drug-specific smooth dose effects (splines by drug), (ii) treatment duration included as a covariate to account for variability in follow-up time across trials, and (iii) a study-level random intercept to account for between-trial heterogeneity

Seven patients developed PHLF, of whom 3 died from liver failure

J Hematol Oncol 2019;12:34 30