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In brain ischemiareperfusion injury, using PARP-1 inhibitors (such as PJ-34, Olaparib) can mitigate H 2 O 2 /O/OH accumulation, prevent neuronal damage, and enhance neurological recovery [253]
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Hsieh, M., Lee, C., Chueh, H., Chang, G., Huang, H., Lin, Y., & Pang, J
Jupyter notebooks used for the data processing and analysis are available on Github ( and archived on Zenodo ( Additional information required to reproduce the analyses is available from the lead contact upon request
The CYP2J2 gene is important in the metabolism of arachidonic acid into either pro- or anti-inflammatory lipid signals
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