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Authors contributions RB and YC wrote the final code for the model

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Due to the wide-ranging impact of the COVID-19 pandemic, there has been a renewed interest in proactive vaccinology , in which research efforts are concentrated on designing vaccines that can induce immunity that would cross-protect against future zoonosis

Mol Cell Endocrinol 93 : 193198 Resnicoff M, Sell C, Rubini M, Coppola D, Ambrose D, Baserga R, Rubin R (1994) Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors

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