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The range of uses for the thiazide and thiazide-like diuretics includes hypertension, congestive heart failure, edema, nephrogenic diabetes insipidus, and nephrocalcinosis (renal stones composed of calcium oxalate or calcium phosphate)

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GLP-1s are often used and covered as first-line diabetes interventions, and as newer GLP-1 products proved to be especially effective, the lines between brands and indications began to blur, ushering in the diabesity dynamic

For instance, those with high physical activity may benefit from slightly higher doses, whereas people with pre-existing medical conditions may need to lower the dosage accordingly

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