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Further investigations of inherent variations of the GIPR within the normal population reveal that the missense GIPR variant, rs1800437 (Glu354Gln) that results in diminished GIPR signalling, leads to lower BMD and increased risk of non-vertebral fractures in perimenopausal Danish women

Tighter rules could also result in fewer employees accessing the medication or shifting costs elsewhere in the healthcare plan

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However, there are some more serious side effects to be aware of, such as pancreatitis (inflammation of the pancreas) and thyroid tumors, although these are rare