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Some early work reported favorable effects on fat metabolism, while larger later trials did not produce the weight loss outcomes needed for approval as an obesity drug

Vitamin B12 Cyanocobalamin Injection by American Regent is a sterile solution used to treat vitamin B12 deficiency and prevent associated conditions such as pernicious anemia and neurological disorders

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Joint pain may involve cartilage, ligaments, tendons, nerves, autoimmune conditions, or referred pain

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A later Phase 2/3 trial (NCT00444613) in Japan investigated one of two doses of Rozebalamin (25 mg or 50 mg) against a placebo, given twice weekly for 3.5 years