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Glutathione prevents high glucose-induced pancreatic fibrosis by suppressing pancreatic stellate cell activation via the ROS/TGF/SMAD pathway
Strikingly, a 55% decrease in E2f1 mRNA levels was sufficient to blunt GSIS (Figures 3A and 3B)
At the time, the pharmaceutical options were dismal
Springer International Publishing, pp 6990
Litigation against a $10 billion-per-year drug like Humira or Revlimid can generate returns that dwarf legal costs by orders of magnitude
Limitations Side effects can be more pronounced initially (nausea, diarrhea)
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