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In contrast to other GPxs, GPx4 is the only one that reduces the hydroperoxides of lipoproteins and complex lipids, such as cholesterol, cholesterol esters, and phospholipids [108], to protect mitochondrial ATP generation from oxidative damage [109]
( Reference Taes, Delanghe and De Vriese 6 ) also detected significant reductions in plasma Hcy levels in a group of nephrectomised rats fed 2 % creatine for 2 weeks, as well as a significant negative correlation between Hcy and plasma creatine
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