GLP-1 receptor agonists are a class of medications that mimic a hormone naturally produced in your gut called glucagon-like peptide-1
In type 2 diabetes mellitus (T2DM), hyperglycemia is a common effect of uncontrolled diabetes and over time leads to serious damage to many of the bodys systems, especially the nerves and blood vessels
Alongside dramatic weight reduction, participants showed impressive improvements in metabolic markers, including significant reductions in blood glucose levels, HbA1c normalization, improved lipid profiles, and substantial reductions in systemic inflammation markers like C-reactive protein (CRP)
GLP-1s are FDA-approved for weight management in appropriate patients, but they aren't right for everyoneyour clinician screens your history and risks (including key contraindications like certain thyroid cancers/MEN2)
Tirzepatide works slightly differently by targeting both GLP-1 and GIP receptors
Research also suggests that by facilitating weight loss, GLP-1 medication can indirectly reduce the burden on your other systemshelping to improve symptoms of PCOS, knee osteoporosis, sleep Apnea and even substance use disorders