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Exploring the efficacy of Wenshentiaojing decoction in PCOS: network pharmacology and mouse model insights

Patients average 10% weight loss in 3 months up to 13% with GLP-1 support

During this period, people typically experience a more consistent reduction in appetite, leading to decreased calorie intake

Hyperoxia decreases glycolytic capacity, glycolytic reserve and oxidative phosphorylation in MLE-12 cells and inhibits complex I and II function, but not complex IV in isolated mouse lung mitochondria

Researchers modified two amino-acid positions to produce a more stable and biologically active analogue

The research was funded by Pentelutes discretionary funds at MIT and the National Cancer Institute at the National Institutes of Health