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LONG R3IGF-I as a more potent alternative to insulin in serum-free culture of HEK293 cells
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Together, these advances highlight a shift toward a systems-level framework in PD biomarker discovery, where microbial dysbiosis, metabolite fluctuations, immune signatures, and -synuclein seeding activity are viewed as interconnected outputs of the gutimmunebrain network rather than isolated signals
Fan X, Zhang X, Liu LC, Zhang S, Pelger CB, Lughmani HY, Haller ST, Gunning WT 3rd, Cooper CJ, Gong R, et al