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However, up to 89% of participants taking efinopegdutide experienced gastrointestinal adverse events (mostly nausea, vomiting and diarrhoea) relative to 28% taking placebo and 60% taking liraglutide (86)
However, the precise effect of GLP-1 on fracture risk has not been unambiguously defined
Using some naive assumptions here (that the average weight loss required for the average obese persons BMI to be below 30 and thus not categorized as obese, assuming x% of obese people take the drug and all experience the average reduction in body weight), we can see a picture emerge that shows the potential to disrupt a trend thats been forming for the past 50 years
This can lead to issues like: High blood sugar Insulin resistance Constant hunger or cravings So, researchers developed GLP-1 receptor agonistslab-made drugs that mimic the natural hormone and help your body regulate itself better
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(PubMed) Kuzminski AM, Del Giacco EJ, Allen RH, Stabler SP, Lindenbaum J
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