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Published pre-clinical studies have used FOXO4-DRI to demonstrate that selective elimination of senescent cells in aged mouse models can improve a range of tissue function parameters including fitness, fur density, renal function, and liver function establishing the broader research principle that senescent cell burden contributes meaningfully to ageing tissue dysfunction and that its targeted reduction produces measurable functional benefits in experimental models

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Con respecto al ejercicio de alta intensidad, existen evidencias de que la l-carnitina potencia el ejercicio de alta intensidad al mantener la relacin acetil CoA/CoA constante, lo que permite el flujo continuo a travs del complejo piruvato deshidrogenasa y la prevencin de la acumulacin de lactato