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The gene-synthesized PSD95-(SH3-GK) (427-724) domain was purified using Ni 2+ -affinity chromatography (HiTrap IMAC FF, Cytiva), followed by thrombin digestion and anion-exchange chromatography (HiTrap Q FF, Cytiva)
Diabetes (2010) 59:27819
Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment
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Starting doses for tirzepatide are typically 2.5 mg per week, administered as a subcutaneous injection
Preclinical models show that GLP-1 RAs reduce amyloid- plaque deposition, dampen neuroinflammation, and enhance synaptic plasticity
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