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Our study suggests that the increased expression and nuclear distribution of p53-pS15 in keloids are associated with the promotion of pro-senescence regulation causing the cell cycle arrest and resistance to apoptosis
Upregulation of TALDO, an enzyme linked to the pentose phosphate pathway enzyme which generates NADPH a key co-factor involved in anti-oxidant pathways, could suggest heightened levels oxidative stress (Ciregia et al., 2019
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