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The trial data is built on the standard ladder (Jastreboff et al., 2022)
It can result from reduced caloric intake, the body adapting to different energy sources, or dehydration from reduced fluid intake alongside reduced food intake
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A provider with a higher starting price but flat or slowly increasing dose-dependent pricing may be significantly more affordable over the full treatment cycle than a provider with a low starting price that escalates sharply at higher doses
8 Blood glucose monitoring is required in these patients and reductions in sulfonylurea or insulin dosing may be necessary (see: Prescribing empagliflozin for guidance on dose adjustments)
Treatment may include GLP-1 injections such as Semaglutide or Liraglutide, which work by increasing fullness, reducing cravings, and supporting sustainable weight management over time
