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406 Therefore, endogenous GLP-1R signaling in astrocytes plays a critical role in maintaining mitochondrial homeostasis and is dependent on FGF21 to effectively regulate glucose metabolism
In clinical studies, it has been administered in doses between 0.5mcg/kg and roughly 16,000mcg/kg for up to 2 weeks [42, 43]
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UVvis spectra were acquired using a Multiskan SkyHigh microplate spectrophotometer (ThermoFisher Scientific) and 96-well plates (Corning) or quartz cuvettes using SkanIt software
Science 300 , 2055 (2003)
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