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2 GLP-1 is an incretin hormone produced by intestinal L cells that is responsible for up to 70% of insulin secretion in response to nutrient intake
Jafari-Vayghan, H., Varshosaz, P., Hajizadeh-Sharafabad, F., Razmi, H
Knowing what not to do is the other half
This is primarily driven by the GLP-1 receptor-mediated slowing of gastric emptying and the central appetite signaling effects that retatrutide shares with semaglutide and tirzepatide
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The increased demand for GLP1 drugs outpaced the supply
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