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In preclinical models, BPC-157 is investigated for its activity across several interconnected signaling cascades, including the VEGFR2/eNOS angiogenic axis, the FAK-paxillin pathway in tendon fibroblasts, and ERK1/2-mediated transcription factor activation
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Kim HJ, Oh GS, Shen A, Lee SB, Khadka D, Pandit A,
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Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide
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