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( d ) Brain-wide Fos expression over area across three groups of mice: WT:Gnas fl/fl [saline] (n = 4 mice), WT:Gnas fl/fl [sema] (n = 7 mice), Glp1r-ires-cre:Gnas fl/fl [sema] (n = 5 mice)

Despite decades of public health efforts, obesity rates continue to climb in nearly every country

Researchers have discovered that GIP is crucial in regulating vascular and cardiac function and lipid metabolism

The focus of this review, however, is the biology of intestinal BTRs, and in particular their relevance to the secretion of gastrointestinal hormones from enteroendocrine cells