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Integrative biomarkers encompass several biological indicators, including as epigenetic, proteomic, genomic, and metabolomic profiles, which might elucidate the fundamental mechanisms of reproductive health and disease (157)

Rare systemic effects have also been observed in experimental models

We also found genetically predicted higher acetyl-carnitine was associated with lower HDL-cholesterol in men and possibly also in women (Additional file 2: Fig

Some peptides may indirectly influence metabolism, which can impact thyroid balance

Effects of a plant-based high-carbohydrate/high-fiber diet versus high-monounsaturated fat/low-carbohydrate diet on postprandial lipids in type 2 diabetic patients