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Oral: SMD, 0.02
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Without adequate L-Carnitine, fatty acids remain trapped in the cellular cytoplasm, unable to be utilized for fuel, leading to a severe bottleneck in energy production
A 2012 Cochrane Review of pooled data from three trials examining tracheostomy-free survival in 974 patients treated with riluzole and 503 placebo-treated patients demonstrated a statistically significant increase in survival from 11.8 months to 14.8 months, but without any benefit on measures of muscle strength
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