For context on how GHK-Cu compares to other anti-aging approaches, see our guide on GHK-Cu copper peptide research and our article on best peptides for longevity and anti-aging research
Common side effects include nausea, vomiting, and diarrhea, which usually subside as your body adjusts to the medication
It is not scheduled under the Controlled Substances Act, but products marketed as "MK-677" capsules or powders are unapproved drugs under FDA rules, and in practice it is sold almost exclusively online as an unregulated "research chemical" labeled not for human consumption
This last analysis was added to explore if outcomes might be related to other medications added during follow up, rather than GLP1-RA or DPP4i use

Trigger Beverages Coffee (both regular and decaffeinated) Alcohol Carbonated beverages (soda, sparkling water) Mint tea (surprisingly, mint can relax the valve between your stomach and esophagus) Other Common Triggers Chocolate Onions and garlic (especially raw) Peppermint Foods That Are Easier on Your Stomach Focus on foods that are less likely to trigger reflux: Lean Proteins Skinless chicken breast Turkey Fish (baked or grilled, not fried) Egg whites Whole Grains Oatmeal Brown rice Whole grain bread Quinoa Vegetables (non-acidic) Leafy greens Broccoli Cauliflower Cucumbers Green beans Potatoes (baked or boiled, not fried) Fruits (non-citrus) Bananas Melons Apples Pears Healthy Fats in Moderation Avocado (small amounts) Olive oil (used sparingly) Nuts and seeds (small portions) Lifestyle Modifications Stay Hydrated Drink plenty of water throughout the dayaim for more than 2-3 liters daily
Earlier years of data to enable a longer lookback period were not available for this analysis