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doi: 10.1016/j.bcmd.2014.06.006

Conclusion Building upon the physiological roles of gut-brain axis hormones and their modulation by bariatric surgery, this review places greater emphasis on the underlying signaling mechanisms, particularly the intracellular pathways activated by these hormones in both central and peripheral tissues

Similarly, for kidney health, the FLOW trial demonstrated that semaglutide reduced the risk of severe kidney outcomes, including kidney failure and death, by 24% (HR 0.76, 95% CI 0.660.88)

Effect of Glucagon on Food Intake and Body Weight in Man