Unlike older secretagogues, Ipamorelin demonstrates strong receptor specificity in research models
Exfoliating acids and retinoids are helpful for addressing fine lines and wrinkles
Health Canada typically reviews new drug applications following FDA approval, adding 6-18 months to Canadian availability timelines
And Wegovy and Zepbound are for obesity
Some patients experience significant appetite suppression and satiety improvements at 0.5 mg or 0.75 mg and maintain that benefit for months without needing more
Nevertheless, in a network meta-analysis comparing short-acting and long-acting GLP-1RAs when used in conjunction with basal insulin, long-acting GLP-1RAs resulted in significantly greater reductions in glycated hemoglobin (HbA1c), fasting plasma glucose, and body weight compared to short-acting GLP-1RAs, with better gastrointestinal tolerability [15]