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Participants showed significant reductions in waist circumference, systolic and diastolic blood pressure, glycated hemoglobin, fasting glucose, insulin levels, and lipid profiles

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Gut microbiota DPP4-like enzymes are increased in type-2 diabetes and contribute to incretin inactivation

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A clinical trial published in 2015 found that participants lost an average of 7.9 per cent of their starting weight in just over a year

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Additionally, GLP-1 receptor activation in the central nervous system reduces appetite and food intake, slows gastric emptying, and promotes satietymechanisms that contribute to both glycemic control and weight reduction

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