Early pharmacology studies characterized it as a ghrelin-receptor agonist with selective growth-hormone-releasing activity in the experimental systems studied
As with the intramuscular route, the kinetics of absorption are dependent on local and regional blood flow, and may be markedly reduced in shock
So the benefit is real, but it is indirect and it depends on whether you were low to begin with
Steimbach and J
Side Effects and Complications NAD+ Infusion Symptoms Nausea, abdominal discomfort or cramping, chest pressure or tightness, flushing, dizziness, headache, chills, shaking, vomiting, and fatigue have been reported with injectable NAD+ products or commercial infusions
Fantin VR, et al