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Originally developed for managing type 2 diabetes, it works by mimicking a hormone in your body that helps regulate appetite and food intake

This dual effect on both sides of the energy balance equation is why retatrutide produced the highest weight loss percentages of any single-agent trial

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Semaglutide Once Weekly as Add-on to SGLT-2 Inhibitor Therapy in Type 2 Diabetes (SUSTAIN 9): A Randomised, Placebo-Controlled Trial

Suspected side effects may also be reported directly via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk) or the Yellow Card app

Injectable appearance comparison Both medications, in their FDA-approved injectable forms, appear as clear solutions when examined in the pen