The findings deliver early evidence that semaglutide may offer a dual benefit, targeting obesity and key reproductive challenges associated with the condition, including irregular menstruation and impaired fertility. Clare Thompson, MBBS, BSc, nMRCGP Separately, a review of five randomized controlled trials presented at ENDO 2026 found that GLP-1 drugs, such as semaglutide and liraglutide, do not appear to harm male fertility and may even improve testosterone levels and sperm quality in some men with obesity
This review summarizes the published clinical and experimental evidence of how insulin interacts with PDA to promote hyperinsulinemia, PDA initiation, and progression
This study included 7,010 adults with diabetes treated with insulin and GLP-1s with over 300,000 treated with insulin and no GLP-1s
Be skeptical of guaranteed weight loss claims
AST serves as a simple, quick, and low-cost screening method, while it may lack the sensitivity to detect transient or subtle autonomic abnormalities
Its job is to tell the pituitary gland to release more growth hormone