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Product Specifications Form: Lyophilized powder Amount: 10mg total (5mg CJC-1295 No DAC + 5mg Ipamorelin) Purity: 98% Appearance: White to off-white powder Molecular Information CJC-1295 No DAC Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Gly-Ser Ipamorelin Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH CAS (CJC-1295 No DAC): 863288-34-0 CAS (Ipamorelin): 170851-70-4 Research Applications Peptide-receptor interaction research Cellular signaling pathway investigations Neuroendocrine pathway research models Multi-peptide interaction studies in controlled laboratory environments Storage Store lyophilized material in a cool, dry environment

Introduction The presence of type 2 diabetes or maternal obesity during pregnancy increases the risk of adverse pregnancy outcomes and birth defects ( In a non-pregnant patient with type 2 diabetes, a GLP-1 agonist or SGLT2 inhibitor can be prescribed if adequate glycemic control is not achieved with metformin, sulphonylureas or (basal) insulin, or if weight reduction, hypoglycemia prevention or reduction of cardiovascular risk is the treatment goal ( Despite the fact that these novel glucose lowering medications have seen wide uptake in clinical practice, information regarding the safety of GLP-1 agonists and SGLT2 inhibitors during pregnancy and lactation is exceedingly scarce

The placenta has endocrine functions, orchestrates maternal adaptations to pregnancy at different periods of pregnancy, and acts as a selective barrier to minimize exposure of developing fetus to xenobiotics, pathogens, and parasites

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236 (1), R29R42

Lilly PACKAGE LABEL - Zepbound Multi-Dose Vial - 10 mg/0.6 mL Dose (40 mg/2.4 mL [16.7 mg/mL]) Rx Only NDC 0002-6304-11 Zepbound (tirzepatide) injection 40 mg/2.4 mL (16.7 mg/mL) ATTENTION: Contains 4 doses of 10 mg/0.6 mL 2.4 mL MULTI-DOSE VIAL For Subcutaneous Use Needles and Syringes are not included Dispense enclosed Medication Guide to each patient