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That single human study was a 12-patient retrospective case series of intra-articular BPC-157 injection for chronic knee pain, in which 7 of 12 patients (58%) reported self-described relief lasting more than 6 months

A more effective approach is timing the injection 3060 minutes after a moderate-fat meal and staying well-hydrated

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Elevated NNMT expression has been observed in adipose tissue of animals with insulin resistance, and modulation of this enzyme has been shown to influence weight and metabolic function in preclinical models

Secondary efficacy outcomes included periodontal probing depth (PD), gingival recession (GR), tooth mobility (TM), bleeding on probing (BOP), and bone defect depth (BDD) at 6 months post-treatment