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Inhibiting the system xC(-)/glutathione axis selectively targets cancers with mutant-p53 accumulation
Such an imbalance is responsible for severe damage to essential biomolecules, such as lipids (lipid peroxidation), proteins (oxidation and inactivation), and DNA (strand breakage and mutations), which is associated with the pathogenesis of numerous diseases, including cancer, neurodegenerative diseases, cardiovascular diseases, and the aging process [28]
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Retrieved November 15, 2021
They are involved in numerous bodily functions, including hormone regulation, immune response, and tissue repair
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