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This causes high oxidative stress, mitochondrial dysfunction, and cell death of the hepatocytes.[ref] As these cells die, inflammatory cascades perpetuate the oxidative stress, leading to bleeding, fibrosis, or possibly liver failure

Drug-Disease Interactions: Rybelsus 14 mg Tablet may interact with disease conditions, including suicidal behaviour and ideation, thyroid cancer, GI adverse events, hypoglycaemia, pancreatitis and retinopathy

Li Z, Ke H, Wang Y, et al

On the other hand, Ozempic is FDA approved to treat Type 2 diabetes, although it is sometimes prescribed off-label for weight loss

The ketogenic diet has demonstrated reductions in triglycerides, improvements in HDL cholesterol, and reductions in small dense LDL particles, the type most associated with cardiovascular risk

doi: 10.1111/obr.13929, 7 Bernosky-SmithK