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Like all medications, they carry potential side effects and should only be taken when prescribed appropriately

Instead, compounded GLP-1 + GIP alternatives may be prescribed when clinically appropriate and legally permissible

Glucagon raises hepatic glucose output but also increases resting energy expenditure and lipolysis

For context on the absorption targets this disrupts, see the carbs-per-hour guide (6090 g/hr for gut-trained athletes) and the 1:0.8 ratio that unlocks that upper end both become harder to hit at race intensity while on GLP-1

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The weight loss tends to be gradual and sustained, which is important for long-term health benefits and maintenance of results