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Notably, despite showing 1.5-fold greater cumulative product yields than FAST-PETase at 40C, TfH-FPE displayed counterbalanced kinetic properties with a threefold reduction in hydrolysis rate but 4.1-fold higher PET binding affinity

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Excess iron is stored in ferritin, a multimer composed of heavy and light chains, which sequesters iron to prevent its toxic accumulation [16]