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The logic behind this approach is that the concomitant activation of GLP1 and estrogen receptors may drive additional favorable effects, when compared with the individual activation of these pathways, which are known to conduct, on their own, beneficial metabolic actions on energy and glucose homeostasis 52

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Gastroenterology &amp

53 Better T2D control and weight reduction with GLP-1 RA therapy may be beneficial in terms of patient-reported health status among the HF cohort