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Sterile alpha and toll-interleukin receptor-containing motif (SARM1) inhibitors Building on the therapeutic potential of modulating NAD + pathways, attention has also turned to SARM1, a pivotal enzyme in axon degeneration, functioning through its NAD + hydrolase activity

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Heo Y, Ishimoto N, Jeon YE et al (2022) Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface

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The practical consequence of yesterday's vote, if the FDA ultimately follows the recommendation through rulemaking, is that licensed physicians could write prescriptions for these peptides and patients could obtain them through regulated compounding pharmacies instead of through the unregulated online gray market