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Trulicity (dulaglutide) is a once-weekly injection for type 2 diabetes that holds approval for cardiovascular risk reduction

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Positive outcomes were also observed in studies investigating associations between GLP-1 RAs and prostate cancer (lower risk in meta-analyses), while breast cancer shows no effect

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A total of 1,961 adult participants with a BMI of at least 30 or at least 27 with at least one weight-related comorbidity were randomized to receive either semaglutide (2.4 mg) or placebo, administered subcutaneously once weekly, along with lifestyle intervention