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These nanosystems offer a transformative platform for enhancing the pharmacological and biopharmaceutical performance of various drugs, including GLP-1 receptor agonists, which are otherwise limited by poor oral bioavailability, enzymatic degradation, and rapid renal clearance

It has been established that l-carnitine alleviates muscle injury and lowers signs of cellular damage and free radical production while also attenuating muscular discomfort

Cardiolipin in the outer membrane also facilitates the transformation of multiple amyloidogenic proteins into pore-forming oligomers that can disrupt the membrane potential, leading to destruction of the mitochondrion, and, in the extreme case, initiation of an apoptotic cascade

Acetyl-L-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the Wisconsin Oncology Network

Barber MJ et al

These receptors are widely distributed across multiple organ systems, which explains the diverse therapeutic effects of this drug class