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Possible reasons include lower calorie intake, changes in dopamine pathways that affect energy and pleasure, and dehydration or poor nutrition

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Moringa is not known to be a major CYP3A4, CYP2C9, or CYP2D6 inhibitor, and semaglutide has minimal hepatic metabolism

The levels of both are extremely low in our SKO mice, consistent with the fact that we are unable to identify and dissect any white adipose tissue (WAT) depots (22)