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The next frontier in GLP-1 drug development GLP-1 medications have already reshaped obesity management, but research pipelines suggest that what we have today is just the beginning

GEP44 activates insulin-independent glucose uptake in muscle tissue via its interactions with Y1-R Despite the positive ISR data and hypothesis that GEP12 would prove superior to GEP44, we noted in in vivo studies (vide infra) that it was considerably inferior to GEP44 in terms of food intake and body weight reduction